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CLK8
Axon 3224
CAS:
898920-65-5
Purity:
98%
- Soluble in DMSO
- MF: C29H26N2O6
- MW: 498.53
Description
CLK8, a specific CLOCK-binding small molecule, inhibits the interaction between CLOCK and BMAL1 and interferes with nuclear translocation of CLOCK both in vivo and in vitro. CLK8 can be used to enhance circadian rhythm.
More Information
| Parent CAS No. | 898920-65-5 |
|---|---|
| Chemical Name | 2-[2-(8,8-Dimethyl-2-oxo-4-phenyl-9,10-dihydropyrano[2,3-f]chromen-5-yl)oxyacetamido]benzamide |
| SMILES | O1C2C3CCC(C)(C)OC=3C=C(OCC(=O)NC3C(C(=O)N)=CC=CC=3)C=2C(C2C=CC=CC=2)=CC1=O |
| MFCD | N.A. |
| InChi | InChI=1S/C29H26N2O6/c1-29(2)13-12-19-22(37-29)15-23(35-16-24(32)31-21-11-7-6-10-18(21)28(30)34)26-20(14-25(33)36-27(19)26)17-8-4-3-5-9-17/h3-11,14-15H,12-13,16H2,1-2H3,(H2,30,34)(H,31,32) |
| InChiKey | SVELPNHVEDZZRQ-UHFFFAOYSA-N |
| CID | 4869040 |
| Short Description | CLOCK/BMAL1 inhibitor |
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