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SP-8008
- Soluble in 0.1N NaOH(aq) and DMSO
- MF: C15H14O6
- MW: 290.27
Description
SP-8008 is a potent and selective inhibitor of SIPA with an IC50 value of 1.44 μM. Moreover, SP-8008 is a modulator of vWF-GP Ib interactions. Importantly, SP-8008 exerted significant antithrombotic effects in vivo in both shear stress-specific and arterial thrombosis, without prolonging bleeding time.
More Information
| Parent CAS No. | 2088247-61-2 |
|---|---|
| Chemical Name | 2-Ethyl-4-oxo-4H-pyran-3-yl 4-hydroxy-3-methoxybenzoate |
| SMILES | C1C=C(C(=O)OC2C(=O)C=COC=2CC)C=C(OC)C=1O |
| MFCD | N.A. |
| InChi | InChI=1S/C15H14O6/c1-3-12-14(11(17)6-7-20-12)21-15(18)9-4-5-10(16)13(8-9)19-2/h4-8,16H,3H2,1-2H3 |
| InChiKey | NHGPHSDMEIUFCL-UHFFFAOYSA-N |
| CID | 126679373 |
| Short Description | SIPA inhibitor |
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