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A2793
- Soluble in DMSO
- MF: C13H12ClNO3
- MW: 265.69
Description
A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK) and TASK-1. A2793 may be considered as a tool to discriminate between the resting and activated channels in heterologous expression systems, and to block TRESK activated by calcineurin in the native cells, which do not express TASK-1.
More Information
| Parent CAS No. | 88349-90-0 |
|---|---|
| Chemical Name | Ethyl 2-(5-chloroquinolin-8-yloxy)acetate |
| SMILES | C12N=CC=CC=1C(Cl)=CC=C2OCC(=O)OCC |
| MFCD | N.A. |
| InChi | InChI=1S/C13H12ClNO3/c1-2-17-12(16)8-18-11-6-5-10(14)9-4-3-7-15-13(9)11/h3-7H,2,8H2,1H3 |
| InChiKey | JEMXUSHXYOXNFL-UHFFFAOYSA-N |
| CID | 21933492 |
| Short Description | TRESK/TASK-1 inhibitor |
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