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CID 11654378

 - FMS inhibitor compound 8  - FMS inhibitor compound 1b
Axon 2061
CAS:  885704-21-2
Purity:  99%
  • Soluble in DMSO
  • MF:  C23H30N6O
  • MW:  406.52

Description

A highly potent FMS kinase inhibitor (IC50 = 0.8 nM); a proof-of-concept candidate in a collagen-induced model of arthritis in mice

More Information

Parent CAS No. 885704-21-2
Chemical Name 4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide
SMILES N1C=C(C#N)C=C1C(NC1=CC=C(N2CCN(C)CC2)C=C1N1CCC(C)CC1)=O
MFCD MFCD22124465
InChi InChI=1S/C23H30N6O/c1-17-5-7-29(8-6-17)22-14-19(28-11-9-27(2)10-12-28)3-4-20(22)26-23(30)21-13-18(15-24)16-25-21/h3-4,13-14,16-17,25H,5-12H2,1-2H3,(H,26,30)
InChiKey DXPSQKSTVIVZLV-UHFFFAOYSA-N
CID 11654378
Short Description FMS receptor tyrosine kinase inhibitor

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