List of publications using VE 821 (Axon 1893) purchased from Axon Medchem
(Total 34 publication citations; up to date up to April 2020)
https://www.embopress.org/doi/full/10.15252/embr.201948460
2019
Landsverk, H. B., Sandquist, L. E., Sridhara, S. C., Rødland, G. E., Sabino, J. C., de Almeida, S. F., ... & Syljuåsen, R. G. (2019). Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1. Nucleic acids research, 47(4), 1797-1813.
https://academic.oup.com/nar/article/47/4/1797/5239026
Mengwasser, K. E., Adeyemi, R. O., Leng, Y., Choi, M. Y., Clairmont, C., D’Andrea, A. D., & Elledge, S. J. (2019). Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets. Molecular cell, 73(5), 885-899.
Permata, T. B. M., Hagiwara, Y., Sato, H., Yasuhara, T., Oike, T., Gondhowiardjo, S., ... & Shibata, A. (2019). Base excision repair regulates PD-L1 expression in cancer cells. Oncogene, 1.
Fordham, S. E., Blair, H. J., Elstob, C. J., Plummer, R., Drew, Y., Curtin, N. J., ... & Pollard, J. (2018). Inhibition of ATR acutely sensitizes acute myeloid leukemia cells to nucleoside analogs that target ribonucleotide reductase. Blood Advances, 2(10), 1157-1169.
Veppil Muralidharan, Somsundar. Thesis. (2016).
https://gupea.ub.gu.se/bitstream/2077/41548/1/gupea_2077_41548_1.pdf
*AZ20 and VE821 from Axon Medchem
VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation.
H Fujisawa, NI Nakajima, S Sunada, Y Lee, H Hirakawa, H Yajima, A Fujimori, M Uesaka and R Okayasu.
Radiation Oncology, 2015,10, 175.
FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2.
M Castella, C Jacquemont, EL Thompson, JE Yeo, RS Cheung, JW Huang, A Sobeck, EA Hendrickson, T Taniguchi.
PLoS Genet 2015, 11, e1005563.
RNA Polymerase III Regulates Cytosolic RNA: DNA Hybrids and Intracellular MicroRNA Expression.
CX Koo, K Kobiyama, YJ Shen, N LeBert, S Ahmad, M Khatoo, T Aoshi, S Gasser and KJ Ishii.
J. Biol. Chem, 2015, 290, 7463-7473.
Genome-Derived Cytosolic DNA Mediates Type I Interferon-Dependent Rejection of B Cell Lymphoma Cells.
YJ Shen, N Le Bert, AA Chitre1, CX Koo, XH Nga, SSW Ho, M Khatoo, NY Tan, KJ Ishii, S Gasser.
Cell Reports, 2015, 11 (3), 460–473. doi:10.1016/j.celrep.2015.03.041
2014
The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair.
S Henriksson, H Rassoolzadeh, E Hedström, C Coucoravas, A Julner, M Goldstein, G Imreh, B Zhivotovsky, MB Kastan, T Helleday and M Farnebo.
Genes & Dev. 2014. 28: 2726-2738. doi: 10.1101/gad.246546.114
N-nitroso-N-ethylurea activates DNA damage surveillance pathways and induces transformation in mammalian cells.
S Bodakuntla, S Sural, P Trivedi, M Lahiri.
BMC cancer, 2014, 14(1), 287.
The Role of Base Excision Repair and Mismatch Repair Proteins in the Processing of Cisplatin Interstrand Cross-Links.
Akshada Sawant, 2014
PhD Thesis, The University of Toledo.
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
KVM Huber, E Salah, B Radic, M Gridling, JM Elkins, A Stukalov, AS Jemth, C Göktürk, K Sanjiv, K Strömberg, T Pham, U Berglund, J Colinge, KL Bennett, JI Loizou, T Helleday, S Knapp & G Superti-Furga.
Nature 2014, 508, 222–227. | doi:10.1038/nature13194
RAE-1 ligands for the NKG2D receptor are regulated by STING-dependent DNA sensor pathways in lymphoma.
AR Lam, N Le Bert, SSW Ho, YJ Shen, LFM Tang, GM Xiong, JL Croxford, CX Koo, KJ Ishii, S Akira, DH Raulet, S Gasser.
Cancer Res. 2014, 74(8), 2193-2203. | doi: 10.1158/0008-5472
2013
Caffeine suppresses homologous recombination through interference with RAD51-mediated joint molecule formation.
AN Zelensky, H Sanchez, D Ristic, I Vidic, SE van Rossum-Fikkert, J Essers, C Wyman and R Kanaar.
Nucl. Acids Res. 2013, 41 (13), 6475-6489. | doi: 10.1093/nar/gkt375
Ataxia Telangiectasia Mutated (ATM) Is Dispensable for Endonuclease I-SceI-induced Homologous Recombination in Mouse Embryonic Stem Cells.
E Rass, G Chandramouly, S Zha, FW Alt and A Xie.
J. Biol. Chem. 2013, 288, 7086-7095. | doi: 10.1074/jbc.M112.445825
An Inverse Switch in DNA Base Excision and StrandBreak Repair Contributes to Melphalan Resistance in Multiple Myeloma Cells
MML Sousa, KA Zub, PA Aas, A Hanssen-Bauer, A Demirovic, A Sarno, E Tian, NB Liabakk, G Slupphaug.
PLoS ONE 2013, 8(2), e55493. | doi:10.1371/journal.pone.0055493
(This is an incomplete list, updated AUGUST 2017)