List of publications using VE 821 (Axon 1893) purchased from Axon Medchem
(Total 45 publication citations; up to date up to June 2023)
Heijink, A. M., Stok, C., Porubsky, D., Manolika, E. M., de Kanter, J. K., Kok, Y. P., ... & van Vugt, M. A. (2022). Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51. Nature Communications, 13(1), 6722.
2021
Sudhindar, P. D., Wainwright, D., Saha, S., Howarth, R., McCain, M., Bury, Y., ... & Shukla, R. (2021). Hcv activates somatic l1 retrotransposition—a potential hepatocarcinogenesis pathway. Cancers, 13(20), 5079.
Sudhindar, P. D., Wainwright, D., Saha, S., Howarth, R., McCain, M., Bury, Y., ... & Shukla, R. (2021). HCV Activates Somatic L1 Retrotransposition to Influence Hepatocarcinogenesis Beyond Viral Clearance. Cancers.
Permata, T. B. M., Sato, H., Gu, W., Kakoti, S., Uchihara, Y., Yoshimatsu, Y., ... & Shibata, A. (2021). High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells. Journal of radiation research, 62(5), 773-781.
Sharma, V. K., Islam, S., Borkar, J., Mishra, S., Panda, D., Santra, M. K., & Lahiri, M. (2021). ATR facilitates the degradation of Api5 through the ubiquitin-proteasome pathway via FBXW2 to regulate apoptosis upon DNA damage. bioRxiv, 2021-08.
Ninou, A. H., Lehto, J., Chioureas, D., Stigsdotter, H., Schelzig, K., Åkerlund, E., ... & Gustafsson, N. M. S. (2021). PFKFB3 inhibition sensitizes DNA crosslinking chemotherapies by suppressing Fanconi anemia repair. Cancers, 13(14), 3604.
佐藤浩央. (2020). 137. がん免疫応答を制御する DNA 修復応答の解明.
Warmerdam, D. O., Alonso‐de Vega, I., Wiegant, W. W., van den Broek, B., Rother, M. B., Wolthuis, R. M., ... & Smits, V. A. (2020). PHF6 promotes non‐homologous end joining and G2 checkpoint recovery. EMBO reports, 21(1).
2019
Landsverk, H. B., Sandquist, L. E., Sridhara, S. C., Rødland, G. E., Sabino, J. C., de Almeida, S. F., ... & Syljuåsen, R. G. (2019). Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1. Nucleic acids research, 47(4), 1797-1813.
https://academic.oup.com/nar/article/47/4/1797/5239026
Mengwasser, K. E., Adeyemi, R. O., Leng, Y., Choi, M. Y., Clairmont, C., D’Andrea, A. D., & Elledge, S. J. (2019). Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets. Molecular cell, 73(5), 885-899.
Permata, T. B. M., Hagiwara, Y., Sato, H., Yasuhara, T., Oike, T., Gondhowiardjo, S., ... & Shibata, A. (2019). Base excision repair regulates PD-L1 expression in cancer cells. Oncogene, 1.
Fordham, S. E., Blair, H. J., Elstob, C. J., Plummer, R., Drew, Y., Curtin, N. J., ... & Pollard, J. (2018). Inhibition of ATR acutely sensitizes acute myeloid leukemia cells to nucleoside analogs that target ribonucleotide reductase. Blood Advances, 2(10), 1157-1169.
Veppil Muralidharan, Somsundar. Thesis. (2016).
https://gupea.ub.gu.se/bitstream/2077/41548/1/gupea_2077_41548_1.pdf
*AZ20 and VE821 from Axon Medchem
VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation.
H Fujisawa, NI Nakajima, S Sunada, Y Lee, H Hirakawa, H Yajima, A Fujimori, M Uesaka and R Okayasu.
Radiation Oncology, 2015,10, 175.
FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2.
M Castella, C Jacquemont, EL Thompson, JE Yeo, RS Cheung, JW Huang, A Sobeck, EA Hendrickson, T Taniguchi.
PLoS Genet 2015, 11, e1005563.
RNA Polymerase III Regulates Cytosolic RNA: DNA Hybrids and Intracellular MicroRNA Expression.
CX Koo, K Kobiyama, YJ Shen, N LeBert, S Ahmad, M Khatoo, T Aoshi, S Gasser and KJ Ishii.
J. Biol. Chem, 2015, 290, 7463-7473.
Genome-Derived Cytosolic DNA Mediates Type I Interferon-Dependent Rejection of B Cell Lymphoma Cells.
YJ Shen, N Le Bert, AA Chitre1, CX Koo, XH Nga, SSW Ho, M Khatoo, NY Tan, KJ Ishii, S Gasser.
Cell Reports, 2015, 11 (3), 460–473. doi:10.1016/j.celrep.2015.03.041
2014
The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair.
S Henriksson, H Rassoolzadeh, E Hedström, C Coucoravas, A Julner, M Goldstein, G Imreh, B Zhivotovsky, MB Kastan, T Helleday and M Farnebo.
Genes & Dev. 2014. 28: 2726-2738. doi: 10.1101/gad.246546.114
N-nitroso-N-ethylurea activates DNA damage surveillance pathways and induces transformation in mammalian cells.
S Bodakuntla, S Sural, P Trivedi, M Lahiri.
BMC cancer, 2014, 14(1), 287.
The Role of Base Excision Repair and Mismatch Repair Proteins in the Processing of Cisplatin Interstrand Cross-Links.
Akshada Sawant, 2014
PhD Thesis, The University of Toledo.
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
KVM Huber, E Salah, B Radic, M Gridling, JM Elkins, A Stukalov, AS Jemth, C Göktürk, K Sanjiv, K Strömberg, T Pham, U Berglund, J Colinge, KL Bennett, JI Loizou, T Helleday, S Knapp & G Superti-Furga.
Nature 2014, 508, 222–227. | doi:10.1038/nature13194
RAE-1 ligands for the NKG2D receptor are regulated by STING-dependent DNA sensor pathways in lymphoma.
AR Lam, N Le Bert, SSW Ho, YJ Shen, LFM Tang, GM Xiong, JL Croxford, CX Koo, KJ Ishii, S Akira, DH Raulet, S Gasser.
Cancer Res. 2014, 74(8), 2193-2203. | doi: 10.1158/0008-5472
2013
Caffeine suppresses homologous recombination through interference with RAD51-mediated joint molecule formation.
AN Zelensky, H Sanchez, D Ristic, I Vidic, SE van Rossum-Fikkert, J Essers, C Wyman and R Kanaar.
Nucl. Acids Res. 2013, 41 (13), 6475-6489. | doi: 10.1093/nar/gkt375
Ataxia Telangiectasia Mutated (ATM) Is Dispensable for Endonuclease I-SceI-induced Homologous Recombination in Mouse Embryonic Stem Cells.
E Rass, G Chandramouly, S Zha, FW Alt and A Xie.
J. Biol. Chem. 2013, 288, 7086-7095. | doi: 10.1074/jbc.M112.445825
An Inverse Switch in DNA Base Excision and StrandBreak Repair Contributes to Melphalan Resistance in Multiple Myeloma Cells
MML Sousa, KA Zub, PA Aas, A Hanssen-Bauer, A Demirovic, A Sarno, E Tian, NB Liabakk, G Slupphaug.
PLoS ONE 2013, 8(2), e55493. | doi:10.1371/journal.pone.0055493
(This is an incomplete list, updated AUGUST 2017)
