Huang, B., Zeng, Z., Kim, S., Fausto, C. C., Koppitch, K., Li, H., ... & Li, Z. (2024). Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease. Cell Stem Cell, 31(6), 921-939.

 

Sato, S., Hishida, T., Kinouchi, K., Hatanaka, F., Li, Y., Nguyen, Q., ... & Sassone-Corsi, P. (2023). The circadian clock CRY1 regulates pluripotent stem cell identity and somatic cell reprogramming. Cell Reports, 42(6).

* SB202190 and CHIR99021 from Axon Medchem

 

Xia, K. S., Li, D. D., Wang, C. G., Ying, L. W., Wang, J. K., Yang, B., ... & Liang, C. Z. (2023). An esterase-responsive ibuprofen nano-micelle pre-modified embryo derived nucleus pulposus progenitor cells promote the regeneration of intervertebral disc degeneration. Bioactive Materials, 21, 69-85.

 

Fdez, E., Madero-Pérez, J., Ordóñez, A. J. L., Naaldijk, Y., Fasiczka, R., Aiastui, A., ... & Hilfiker, S. (2022). Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement. iScience, 25(6).

 

Sens, J., Hoffmann, D., Lange, L., Vollmer Barbosa, P., Morgan, M., Falk, C. S., & Schambach, A. (2021). Knockout-induced pluripotent stem cells for disease and therapy modeling of IL-10-associated primary immunodeficiencies. Human Gene Therapy, 32(1-2), 77-95.

 

Weinberger, L. (2020). Characterization of human naive pluripotent stem cells and their differentiation to Primordial Germ Cells (Doctoral dissertation, The Weizmann Institute of Science).

* CHIR99021, PD0325901, SB202190, BIRB796, Y27632, CGP77675 from Axon Medchem

 

Jones, D. S., Jenney, A. P., Joughin, B. A., Sorger, P. K., & Lauffenburger, D. A. (2018). Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition. Science Signaling, 11(520), eaal1601.

 

Gafni, O. (2017). Delineating routes and applications of naive pluripotency (Doctoral dissertation, The Weizmann Institute of Science (Israel)).

* SB202190 and BIRB796 from Axon Medchem

 

Hanna, Yaqub; Novershtern, Noa; Rais, Yoach. Media for culturing pluripotent stem cells. U.S. Patent Application No 15/500,163, 2017.

* CHIR99021, BIO, PD0325901, PD98059, PD184352, BAY43-9006, Thiazovivin, CGP77675, DAPT, DBZ, LY2886762, RU-SKI43, LDN193189, K02288, Dosomorphine, BIRB796, AEG3482, SB203580, SB202190, LY 2228820, PD169316 etc. from Axon Medchem

 

Yang, J., Liu, Z., Liu, H., He, J., Yang, J., Lin, P., ... & Yi, Q. (2017). C-reactive protein promotes bone destruction in human myeloma through the CD32–p38 MAPK–Twist axis. Science Signaling, 10(509), eaan6282.

 

Weinberger, L. (2016). Characterization of human naive pluripotent stem cells and their differentiation to Primordial Germ Cells (Doctoral dissertation, The Weizmann Institute of Science (Israel)).

* SB20290 and Y-27632 from Axon Medchem

 

Menon, M. B., Dhamija, S., Kotlyarov, A., & Gaestel, M. (2015). The problem of pyridinyl imidazole class inhibitors of MAPK14/p38α and MAPK11/p38β in autophagy research. Autophagy, 11(8), 1425-1427.

* BIRB-796 and SB201290 from Axon Medchem

 

Tiedje, C., Lubas, M., Tehrani, M., Menon, M. B., Ronkina, N., Rousseau, S., ... & Gaestel, M. (2015). p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex. RNA, 21(2), 262-278.

* BIRB796, SB203580, and SB202190 from Axon Medchem

 

de Bruin, A., Rothuizen, J., Penning, L. C., & Schotanus, B. A. Sathidpak Nantasanti1, Bart Spee1, Hedwig S. Kruitwagen1, Chen Chen1, 2, Niels Geijsen1, 2, Loes A. Oosterhoff1, Monique E. van Wolferen1, Nicolas Pelaez1, Hille Fieten1, Richard W. Wubbolts3, Guy C. Grinwis4, Jefferson Chan5, Meritxell Huch2, 6, Robert RG Vries2, Hans Clevers2, Alain de Bruin4, 7, Jan Rothuizen1, Louis C. Penning1, Baukje A. Schotanus1. Adult Liver Stem Cells in Hepatic Regeneration and Cancer, 45.

* A83-01, Y-27632, and SB202190 from Axon Medchem

 

Gafni, O., Weinberger, L., Mansour, A. A., Manor, Y. S., Chomsky, E., Ben-Yosef, D., ... & Hanna, J. H. (2013). Derivation of novel human ground state naive pluripotent stem cells. Nature, 504(7479), 282-286.

* SB202190, BIRB796, Y-27632, CHIR99021, PD0325901, etc from Axon Medchem

 

Endoplasmic reticulum-associated ubiquitin conjugating enzyme-Ube2j1 is a novel substrate of MAPKAP kinase-2 involved in MK2-mediated TNFalpha production. MB Menon, C Tiedje, J Lafera, N Ronkina, T Konen, A Kotlyarov and M Gaestel. Biochem. J. 2013, in press. doi:10.1042/BJ20130755

* SB202190, BX912 and BIRB796 from Axon Medchem

 

He, J., Liu, Z., Zheng, Y., Qian, J., Li, H., Lu, Y., ... & Yang, J. (2012). p38 MAPK in myeloma cells regulates osteoclast and osteoblast activity and induces bone destruction. Cancer Research, 72(24), 6393-6402.

 

Menon, M. B., Kotlyarov, A., & Gaestel, M. (2011). SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition. PLoS ONE, 6(8), e23054.

* BIRB-796 and SB201290 from Axon Medchem

 

Menon, M. B. (2010). Functional characterization of the p38 MAPK-MK2/3 complex (Doctoral dissertation, Hannover Medical School).

* BIRB796 and SB202190 from Axon Medchem