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CC81

Axon 4488
CAS:  332950-12-6
Purity:  99%
  • Soluble in DMSO
  • MF:  C23H21N3O3S2
  • MW:  451.56

Description

CC81 is an active metabolite of ISR activator compound A8 (Axon 4461) which selectively activates the ISR by binding RIG-I . Unlike A8, the CC81 metabolite does not induce lipid droplet clearance and enhances IFN signaling in the presence of dsRNA.

More Information

Parent CAS No. 332950-12-6
Chemical Name Ethyl 2-(3-amino-4,6-dimethyl-1-thia-7-aza-2-indenylcarbonylamino)-4-phenyl-3-thenoate
SMILES C1(C)=C2C(N)=C(C(NC3=C(C(OCC)=O)C(C4=CC=CC=C4)=CS3)=O)SC2=NC(C)=C1
InChi InChI=1S/C23H21N3O3S2/c1-4-29-23(28)17-15(14-8-6-5-7-9-14)11-30-21(17)26-20(27)19-18(24)16-12(2)10-13(3)25-22(16)31-19/h5-11H,4,24H2,1-3H3,(H,26,27)
InChiKey BPVWCTZLAKMQDH-UHFFFAOYSA-N
Short Description ISR activator

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