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FB231

Name: FB231
SKU: 4451

Axon 4451

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CAS: 2166045-37-8

Purity: 98%

Soluble in DMSO and EtOH

MF: C24H21N5O2
MW: 411.46

Description

FB231 is a Parkin activator which lowers the threshold for mitochondrial toxins to induce PINK1/Parkin-mediated mitophagy.

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Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

Ubiquitin Ligase (E3; other)

Parent CAS No.	2166045-37-8
Chemical Name	N-[1-Phenyl-5-(o-toluoylamino)-1H-1,2,4-triazol-3-yl]-o-toluamide
Short Description	Parkin activator

FB231 Parkin activator FB 231 FB-231 CAS 2166045-37-8 Axon Medchem Axon 4451 Protein degradation Ubiquitin Ligase (E3; other) Parkin Activator Enzymes Mitophagy Parkinson’s disease PINK1 Supplier Vendor

References

WM Rosencrans et al. Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress. Sci Adv. 2025 Aug 29;11(35):eady0240.

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FB231

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