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AGR1.137
Axon 4403
CAS:
N.A.
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C25H28N4O4
- MW: 448.52
Description
AGR1.137 is a negative allosteric modulator of CXCR4 which blocks (both in vitro and in vivo) CXCL12-mediated receptor nanoclustering and cell sensitivity to chemoattractant gradients without altering ligand binding, thus preserving other signaling events.
More Information
| Parent CAS No. | N.A. |
|---|---|
| Chemical Name | Ethyl 1-(4-((4-(4-(hydroxymethyl)phenyl)-1H-1,2,3-triazol-1-yl)methyl)benzoyl)-4-piperidinecarboxylate |
| Short Description | CXCR4 NAM |
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