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PF-05175157
Axon 4378
CAS:
1301214-47-0
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C23H27N5O2
- MW: 405.49
Description
PF-05175157 is an acetyl-CoA carboxylase (ACC) inhibitor with IC50 values of 27 nM and 33 nM for hACC1 and hACC2, respectively.
More Information
| Parent CAS No. | 1301214-47-0 |
|---|---|
| Chemical Name | 1-Isopropyl-1'-((2-methyl-1H-1,3-benzimidazol-6-yl)carbonyl)-4,6-dihydrospiro[indazole-5,4'-piperidin]-7(1H)-one |
| SMILES | C12N(C(C)C)N=CC=1CC1(CCN(C(C3C=CC4N=C(C)NC=4C=3)=O)CC1)CC2=O |
| MFCD | MFCD28502250 |
| InChi | InChI=1S/C23H27N5O2/c1-14(2)28-21-17(13-24-28)11-23(12-20(21)29)6-8-27(9-7-23)22(30)16-4-5-18-19(10-16)26-15(3)25-18/h4-5,10,13-14H,6-9,11-12H2,1-3H3,(H,25,26) |
| InChiKey | BDXXSFOJPYSYOC-UHFFFAOYSA-N |
| CID | 52934180 |
| Short Description | ACC inhibitor |
