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HRX215

 - LN3348  - Darizmetinib
Axon 4195
CAS:  2369583-33-3
Purity:  98%
  • Soluble in DMSO
  • MF:  C21H17F2N5O3S
  • MW:  457.45

Description

HRX215 is a first-in-class, potent, selective and orally active MKK4 inhibitor with an IC50 value of 0.02 µM. HRX215 boosted liver regeneration and prevented liver failure after extensive hepatectomy in pigs.

More Information

Parent CAS No. 2369583-33-3
Chemical Name N-(2,6-Difluoro-3-(5-(pyridin-4-yl)-1H-pyrazolo[3,4-b]pyridine-3-carbonyl)phenyl)propane-1-sulfonamide
MFCD N.A.
Short Description MKK4 inhibitor
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