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DW-71177

Name: DW-71177
SKU: 4131

Axon 4131

CAS: 2241311-72-6

Purity: 99%

Soluble in DMSO

MF: C20H28N6O2
MW: 384.48

Description

DW-71177 is a potent, orally bioavailable and BD1-selective BET inhibitor that exhibits strong antileukemic activity with a Kd value of 6.7 nM for BRD4-BD1.

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Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

BET (BRD)

Parent CAS No.	2241311-72-6
Chemical Name	N-(4-(7-Methoxy-1-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-ylamino)butyl)-3-methylbutanamide
MFCD	N.A.
Short Description	BET inhibitor

DW-71177 BET inhibitor DW71177 DW 71177 CAS 2241311-72-6 Axon Medchem Axon 4131 Histone BET (BRD) Inhibitor Proteins Acute myeloid leukemia Bromodomain and extraterminal domain Supplier Vendor

References

I Ali et al. DW71177: A novel [1,2,4]triazolo[4,3-a]quinoxaline-based potent and BD1-Selective BET inhibitor for the treatment of acute myeloid leukemia. Eur J Med Chem. 2024 Feb 5;265:116052.

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DW-71177

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