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Sobetirome

Name: Sobetirome
SKU: 4126

- GC1 - QRX431

Axon 4126

CAS: 211110-63-3

Purity: 98%

Soluble in 0.1N NaOH(aq), DMSO and EtOH

MF: C20H24O4
MW: 328.4

Description

Sobetirome is a high-affinity subtype-selective agonist ligand for the thyroid hormone receptor with Kd value of 440 pM for hTRα1 and 67 pM for hTRβ1.

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Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

Parent CAS No.	211110-63-3
Chemical Name	2-(4-(4-Hydroxy-3-isopropylbenzyl)-3,5-dimethylphenoxy)acetic acid
MFCD	N.A.
Short Description	TRβ agonist

Sobetirome TRβ agonist GC1 QRX431 GC 1 GC-1 QRX 431 QRX-431 CAS 211110-63-3 Axon Medchem Axon 4126 Triiodothyronine THR Agonist Receptors Thyromimetic compound Supplier Vendor

References

G Chiellini et al. A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. Chem Biol. 1998 Jun;5(6):299-306.

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Sobetirome

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