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N-Carbamyl-L-glutamic acid
- Carglumic acid - Carbamylglutamate
Axon 3816
CAS:
1188-38-1
- Optical Purity: Optically pure
- Soluble in water, 0.1N NaOH(aq), DMSO and EtOH
- MF: C6H10N2O5
- MW: 190.15
Description
N-Carbamyl-L-glutamic acid, a deacylase-resistant analogue of N-acetylglutamate, is a carbamyl phosphate synthetase 1 (CPS1) activator. N-Carbamyl-L-glutamic acid is used to treat primary N-acetyl-L-glutamate synthase deficiency and hyperammonemia associated with organic acidemias such as methylmalonic aciduria, propionic aciduria, and isovaleric aciduria.
More Information
| Parent CAS No. | 1188-38-1 |
|---|---|
| Chemical Name | (S)-2-Ureidopentanedioic acid |
| SMILES | C(=O)(N)N[C@H](C(O)=O)CCC(=O)O |&1:4,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1 |
| InChiKey | LCQLHJZYVOQKHU-VKHMYHEASA-N |
| CID | 121396 |
| Short Description | CPS1 activator |


