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CFT-8634

 - Sendegobresib
Axon 3764
CAS:  2704617-96-7
  • Optical Purity:  0.975
  • Soluble in DMSO
  • MF:  C37H45F3N6O5
  • MW:  710.79

Description

CFT-8634 is a selective orally bioavailable BRD9 degrader.

More Information

Parent CAS No. 2704617-96-7
Chemical Name (S)-3-(4-(4-((S)-1-(2,6-dimethoxy-4-(1,4,5-trimethyl-6-oxo-1,6-dihydropyridin-3-yl)benzyl)-3,3-difluoropiperidin-4-yl)piperazin-1-yl)-3-fluorophenylamino)piperidine-2,6-dione
extra_info Sold in collaboration with Chemietek
SMILES C1N(C2C(F)=CC(N[C@@H]3C(=O)NC(=O)CC3)=CC=2)CCN([C@@H]2C(F)(F)CN(CC3C(OC)=CC(C4=CN(C)C(=O)C(C)=C4C)=CC=3OC)CC2)C1 |&1:8,21,r|
MFCD N.A.
InChi InChI=1S/C37H45F3N6O5/c1-22-23(2)36(49)43(3)19-26(22)24-16-31(50-4)27(32(17-24)51-5)20-44-11-10-33(37(39,40)21-44)46-14-12-45(13-15-46)30-8-6-25(18-28(30)38)41-29-7-9-34(47)42-35(29)48/h6,8,16-19,29,33,41H,7,9-15,20-21H2,1-5H3,(H,42,47,48)/t29-,33-/m0/s1
InChiKey GNRGNRCQXHMQQV-ZQAZVOLISA-N
CID 163203607
Short Description BRD9 degrader

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