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Riluzole
- PK26124
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C8H5F3N2OS
- MW: 234.2
Description
Riluzole is a neuroprotective drug that blocks glutamatergic neurotransmission in the CNS. Riluzole inhibits the release of glutamic acid from cultured neurons, from brain slices, and from corticostriatal neurons in vivo. Riluzole also blocks some of the postsynaptic effects of glutamic acid by noncompetitive blockade of N-methyl-D-aspartate (NMDA) receptors. In vivo, riluzole has neuroprotective, anticonvulsant, and sedative properties. The hydrochloride salt form of Riluzole (Axon 3576) is available from stock as well.
More Information
| Parent CAS No. | 1744-22-5 |
|---|---|
| Chemical Name | 6-(Trifluoromethoxy)benzo[d]thiazol-2-amine |
| SMILES | C1C=C2N=C(N)SC2=CC=1OC(F)(F)F |
| MFCD | MFCD00210213 |
| InChi | InChI=1S/C8H5F3N2OS/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5/h1-3H,(H2,12,13) |
| InChiKey | FTALBRSUTCGOEG-UHFFFAOYSA-N |
| CID | 5070 |
| Short Description | Glutamatergic neurotransmission blocker |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 3473 | (R)-(+)-HA-966 |
From $132.00 |
| 3576 | Riluzole hydrochloride |
From $88.00 |
| 3841 | Dextromethorphan hydrobromide |
From $66.00 |
| 4169 | CIQ |
From $143.00 |
