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Mycophenolate mofetil
- RS61443 - TM-MMF
Axon 3498
CAS:
128794-94-5
Purity:
99%
- Soluble in 0.1N NaOH(aq), 0.1N HCl(aq), DMSO and EtOH
- MF: C23H31NO7
- MW: 433.49
Description
Mycophenolate mofetil is an immunosuppressive prodrug which is hydrolyzed by esterases in the intestine and blood to release mycophenolic acid (MPA). MPA is a potent, selective, noncompetitive inhibitor of the type 2 isoform of inosine monophosphate dehydroxygenase (IMPDH) expressed in activated human T and B lymphocytes.
More Information
| Parent CAS No. | 128794-94-5 |
|---|---|
| Chemical Name | (E)-2-Morpholinoethyl 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate |
| SMILES | C12C(=O)OCC=1C(C)=C(OC)C(C/C=C(C)/CCC(=O)OCCN1CCOCC1)=C2O |
| MFCD | MFCD00867568 |
| InChi | InChI=1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+ |
| InChiKey | RTGDFNSFWBGLEC-SYZQJQIISA-N |
| CID | 5281078 |
| Short Description | IMPDH inhibitor |
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