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BI 749327
Axon 3036
CAS:
2361241-23-6
Purity:
99%
- Soluble in DMSO
- MF: C23H21F3N4O2
- MW: 442.43
Description
BI 749327 is a potent, selective and orally bioavailable TRPC6 inhibitor with IC50 values of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively.
More Information
| Parent CAS No. | 2361241-23-6 |
|---|---|
| Chemical Name | (4-(6-Aminopyridazin-3-yl)piperidin-1-yl)(4-(4-(trifluoromethyl)phenoxy)phenyl)methanone |
| SMILES | C1C(OC2C=CC(C(N3CCC(C4C=CC(N)=NN=4)CC3)=O)=CC=2)=CC=C(C(F)(F)F)C=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C23H21F3N4O2/c24-23(25,26)17-3-7-19(8-4-17)32-18-5-1-16(2-6-18)22(31)30-13-11-15(12-14-30)20-9-10-21(27)29-28-20/h1-10,15H,11-14H2,(H2,27,29) |
| InChiKey | RGYMFGHHIDRCBN-UHFFFAOYSA-N |
| CID | 138377580 |
| Short Description | TRPC6 inhibitor |
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