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PluriSIn #1
- NSC 14613 - Pluripotent cell-specific inhibitor #1
Axon 2091
CAS:
91396-88-2
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C12H11N3O
- MW: 213.24
Description
PluriSIn #1 is a stearoyl-CoA desaturase 1 (SCD1) inhibitor identified as a pluripotent cell-specific inhibitor. It selectively eliminates undifferentiated human pluripotent stem cells by disrupting oleic acid biosynthesis and lipid metabolism.
Residual undifferentiated hPSCs can pose safety concerns in differentiation workflows. PluriSIn #1 is useful for studying lipid metabolic dependencies of pluripotent cells and for removing undifferentiated hPSCs from mixed cultures.
Key Features
- SCD1 inhibitor
- Blocks oleic acid biosynthesis
- Selectively eliminates undifferentiated human pluripotent stem cells
- Useful for pluripotency-dependent lipid metabolism studies
Applications
- hPSC culture quality control
- Stem-cell differentiation workflows
- Pluripotent cell elimination assays
- Lipid metabolism research
More Information
| Parent CAS No. | 91396-88-2 |
|---|---|
| Chemical Name | N'-phenylisonicotinohydrazide |
| SMILES | C1=NC=CC(C(NNC2=CC=CC=C2)=O)=C1 |
| MFCD | N.A. |
| InChi | InChI=1S/C12H11N3O/c16-12(10-6-8-13-9-7-10)15-14-11-4-2-1-3-5-11/h1-9,14H,(H,15,16) |
| InChiKey | HUDWXDLBWRHCKO-UHFFFAOYSA-N |
| CID | 225362 |
| Short Description | SCD1 inhibitor |
