Bulk Inquiry
P2Y14 Antagonist Prodrug 7j hydrochloride
- PPTN Prodrug 7j
- Soluble in water and DMSO
- MF: C33H31F3N2O3.HCl
- MW: 597.07
Description
P2Y14 Antagonist Prodrug 7j hydrochloride (PPTN prodrug 7j) is a highly bioavailable prodrug of the P2Y14 receptor antagonist PPTN (Axon 3420). It is designed to improve systemic exposure while delivering pharmacological antagonism of the UDP-sugar-responsive P2Y14 receptor.
P2Y14 is a purinergic GPCR activated by UDP-sugars and implicated in immune-cell recruitment, mucosal inflammation and inflammatory signaling. P2Y14 Antagonist Prodrug 7j is useful for in vivo-oriented P2Y14 pharmacology and purinergic inflammation research.
Key Features
- Bioavailable prodrug of the P2Y14 antagonist PPTN
- Targets UDP-sugar/P2Y14 receptor signaling
- Useful for purinergic inflammation pharmacology
- Supports studies requiring improved systemic exposure
Applications
- P2Y14 receptor antagonist studies
- Purinergic signaling research
- Inflammation and immune-cell migration models
- In vivo pharmacology assay development
More Information
| Parent CAS No. | 1315308-19-0 |
|---|---|
| Chemical Name | 2-(dimethylamino)-2-oxoethyl 4-(4-(piperidin-4-yl)phenyl)-7-(4-(trifluoromethyl)phenyl)-2-naphthoate hydrochloride |
| SMILES | C1C(C2C=CC(C3CCNCC3)=CC=2)=C2C=CC(C3C=CC(C(F)(F)F)=CC=3)=CC2=CC=1C(=O)OCC(=O)N(C)C.Cl |
| MFCD | N.A. |
| InChi | InChI=1S/C33H31F3N2O3.ClH/c1-38(2)31(39)20-41-32(40)27-18-26-17-25(22-7-10-28(11-8-22)33(34,35)36)9-12-29(26)30(19-27)24-5-3-21(4-6-24)23-13-15-37-16-14-23;/h3-12,17-19,23,37H,13-16,20H2,1-2H3;1H |
| InChiKey | JDYYLENIRWCXNN-UHFFFAOYSA-N |
| CID | 91826492 |
| Short Description | P2Y14 antagonist |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1862 | MRS 2578 |
From $99.00 |
| 3111 | Ticagrelor |
From $66.00 |
| 3420 | PPTN hydrochloride |
From $143.00 |
| 4368 | HDL-16 |
From $99.00 |
