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CGS 9343B
- Zaldaride maleate- Parent CAS: 109826-26-8
- Soluble in DMSO
- MF: C26H28N4O2.C4H4O4
- MW: 544.6
Description
CGS 9343B is an inhibitor of calmodulin activity and Ca2+-calmodulin-dependent signaling.
Calmodulin translates intracellular calcium signals into enzymatic and transcriptional responses through CaM-dependent kinases, phosphatases and ion-channel regulation. CGS 9343B is useful for investigating calmodulin-dependent cellular mechanisms.
Key Features
- Inhibits calmodulin activity
- Blocks Ca2+-calmodulin-dependent signaling
- Useful for calcium-regulated enzyme studies
- Relevant to signal transduction and ion-channel modulation research
Applications
- Calmodulin activity assays
- Ca2+-dependent signaling studies
- CaM kinase and phosphatase pathway research
- Cellular calcium response models
More Information
| Parent CAS No. | 109826-26-8 |
|---|---|
| Chemical Name | 1-[1-(4-Methyl-4H,6H-5-oxa-10b-aza-benzo[e]azulen-4-ylmethyl)-piperidin-4-yl]-1,3-dihydro-benzoimidazol-2-one maleate |
| SMILES | C1OC(CN2CCC(N3C(=O)NC4C=CC=CC3=4)CC2)(C)C2=CC=CN2C2C=CC=CC1=2.C(=O)(O)/C=CC(=O)O |
| MFCD | MFCD04113002 |
| InChi | InChI=1S/C26H28N4O2.C4H4O4/c1-26(24-11-6-14-29(24)22-9-4-2-7-19(22)17-32-26)18-28-15-12-20(13-16-28)30-23-10-5-3-8-21(23)27-25(30)31;5-3(6)1-2-4(7)8/h2-11,14,20H,12-13,15-18H2,1H3,(H,27,31);1-2H,(H,5,6)(H,7,8)/b;2-1- |
| InChiKey | NGODOSILXOFQPH-BTJKTKAUSA-N |
| CID | 6450522 |
| Short Description | Calmodulin inhibitor |
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