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Reboxetine mesylate

Axon 1240
  • Parent CAS:  71620-89-8
Purity:  98%
  • Soluble in DMSO
  • MF:  C19H23NO2.CH4SO3
  • MW:  409.5

Description

Reboxetine mesylate is a selective noradrenaline/norepinephrine reuptake inhibitor (NARI/NRI) that blocks norepinephrine transporter (NET)-mediated uptake.

NET controls synaptic norepinephrine availability and contributes to attention, arousal, mood and autonomic regulation. Reboxetine is useful for studying noradrenergic transporter pharmacology and catecholamine-dependent CNS signaling.

Key Features

  • Selective norepinephrine reuptake inhibitor
  • Targets norepinephrine transporter (NET/SLC6A2)
  • Increases noradrenergic signaling in uptake assays
  • Useful reference compound for NARI pharmacology

Applications

  • NET uptake assays
  • Noradrenergic neurotransmission research
  • Catecholamine transporter selectivity studies
  • Mood and attention pathway models

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