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LY 393558

Axon 1139
CAS:  271780-64-4
Purity:  99%
  • Moderately soluble in DMSO and EtOH
  • MF:  C26H31FN4O4S2
  • MW:  546.68

Description

LY 393558 is a serotonin reuptake inhibitor (SRI) with additional 5-HT1B/5-HT1D receptor antagonist activity. It is useful for studying combined transporter and serotonin receptor modulation.

Compounds that influence both serotonin uptake and 5-HT1B/1D receptor signaling can help dissect presynaptic serotonergic regulation and migraine- or mood-related pathways. LY 393558 is suitable for multi-target serotonergic pharmacology studies.

Key Features

  • Serotonin reuptake inhibitor
  • 5-HT1B/5-HT1D receptor antagonist
  • Multi-target serotonergic ligand
  • Useful for transporter-receptor interaction studies

Applications

  • Serotonin transporter research
  • 5-HT1B/1D receptor pharmacology
  • Serotonergic neurotransmission studies
  • Mood and migraine pathway models

More Information

Certificate of Analysis (B3)
Material Safety Data Sheet (B3)

Certificate of Analysis

B2

Material Safety Data Sheet

B2
Parent CAS No. 271780-64-4
Chemical Name 1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-3-isopropyl-6-methanesulfonyl-3,4-dihydro-1H-benzo[1,2,6]thiadiazine 2,2-dioxide
SMILES N1(CCN2CC=C(CC2)C2C3C(NC=2)=CC(F)=CC=3)C2C=CC(S(=O)(C)=O)=CC=2CN(C(C)C)S1(=O)=O
MFCD MFCD10565930
InChi InChI=1S/C26H31FN4O4S2/c1-18(2)31-17-20-14-22(36(3,32)33)5-7-26(20)30(37(31,34)35)13-12-29-10-8-19(9-11-29)24-16-28-25-15-21(27)4-6-23(24)25/h4-8,14-16,18,28H,9-13,17H2,1-3H3
InChiKey QUSLYAPLTMMCFE-UHFFFAOYSA-N
CID 10347428
Short Description SSRI, 5-HT1B/1D antagonist

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