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N 0734 hydrochloride
Axon 1041
- Parent CAS: 102121-00-6
Purity:
99%
- Moderately soluble in water
- MF: C19H25NOS.HCl
- MW: 351.93
Description
N 0734 hydrochloride is a potent and selective dopamine receptor agonist and a derivative of rotigotine/N-0437. The compound has been described alongside N-0434 and N-0437 as a dopamine agonist lacking significant α2-adrenoceptor activity.
Dopamine receptor agonists that are separated from α2-adrenoceptor activity are useful for dissecting dopaminergic responses from adrenergic effects. N 0734 hydrochloride is applicable in studies of dopamine receptor selectivity and ligand structure-activity relationships.
Key Features
- Potent and selective dopamine receptor agonist
- Derivative of rotigotine/N-0437
- Reported to lack significant α2-adrenoceptor activity
- Useful for dopaminergic selectivity studies
Applications
- Dopamine receptor pharmacology
- Dopaminergic GPCR signaling assays
- Dopamine versus adrenergic selectivity studies
- Structure-activity relationship research
More Information
| Parent CAS No. | 102121-00-6 |
|---|---|
| Chemical Name | 6-[Propyl-(2-thiophen-3-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol hydrochloride |
| SMILES | C1C=C2CC(N(CCC)CCC3C=CSC=3)CCC2=C(O)C=1.Cl |
| MFCD | MFCD12911793 |
| InChi | InChI=1S/C19H25NOS.ClH/c1-2-10-20(11-8-15-9-12-22-14-15)17-6-7-18-16(13-17)4-3-5-19(18)21;/h3-5,9,12,14,17,21H,2,6-8,10-11,13H2,1H3;1H |
| InChiKey | OWYUTBVGLYXNOS-UHFFFAOYSA-N |
| CID | 13564368 |
| Short Description | DA agonist |
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