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Compound 120 - Atazanavir, deuterated | CTP 518

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1753

CAS [N.A.]

MF C38H37D15N6O7.H2O4S
MW 818.03

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO

Compound 120

Description

A partially deuterated analog of Atazanavir (Axon 1441), an oral HIV protease inhibitor; A deuterium-containing medicine with improved ADME properties; Compound 120 showed an approximately 50% increase in half life compared with Atazanavir.

Deuterated Protease inhibitor (see Axon 1441)

Chemical name

(3S,8S,9S,12S)-3-(1,1-dimethylethyl)-12-[1,1-di(methyl-d3)ethyl-2,2,2-d3]-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-Pentaazatetradecanedioic acid, 1,14-di(methyl-d3) ester sulfate

Parent CAS No.

[1092540-56-1]

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Size Unit Price Stock
2 mg €120.00 In Stock
5 mg €180.00 In Stock
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Related Products

Axon ID Name Description From price
1441 BMS 232632 Protease inhibitor €80.00
1553 Nelfinavir mesylate HIV-1 protease inhibitor €90.00
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1669 Danoprevir HCV NS3/4A serine protease inhibitor €90.00
2093 Daclatasvir dihydrochloride Hepatitis C virus (HCV) NS5A protein inhibitor €70.00
2665 Cenicriviroc Oral CCR5-antagonist for treatment of HIV infection €160.00
3483 NBD-556 HIV-1 entry inhibitor; gp120-CD4 interaction blocker €70.00

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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