Stem cell differentiation
All cells within a complex multicellular organism contain the same set of DNA. Different deployment of the eukaryotic genome by epigenetic modulation determines different cellular morphology and function. This process of gene expression is regulated by cues from both within and outside cells. Since epigenetic mechanisms are intrinsically reversible, interdependent, and highly dynamic, they provide the opportunity to differentiate cells in a controlled manor. Axon Medchem has a wide range of products that find their application in the field of cell differentiation.
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Type Axon ID to order.
e.g. for Axon 1836, type 1836
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Axon 2387 - SMI 481
First small-molecule inhibitor (SMI) of the yeast PITP Sec14 -
Axon 1519 - Sunepitron hydrochloride
Anxiolytic and antidepressant drug -
Axon 2289 - ABT 702
The first, non-nucleoside adenosine kinase (ADK) inhibitor -
Axon 2294 - KRCA 0008
Potent and selective dual ALK/ACK1 inhibitor with good drug-like properties
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Axon 2329 - NS 19504
Potent activator of large-conductance Ca2+-activated potassium (BK) channels -
Axon 2404 - TY 52156
Selective, competitive, and orally active S1P3 antagonist -
Axon 2405 - AMG 837
Orally bioavailable partial agonist of GPR40 (FFA1) -
Axon 2374 - Optovin
Reversible photoactivated TRPA1 agonist