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Axon 4309
CAS [102704-40-5]
MF C22H18N2O2MW 342.39
GAT211 is a potent CB1 receptor ago-PAM with allosteric agonist activity residing exclusively in the R-(+)-enantiomer, GAT228 (Axon 4358), and S-(-)-enantiomer, GAT229 (Axon 4359), acting as a “pure” and potent CB1R PAM. GAT211 engages CB1R allosteric site(s), enhances the binding of the orthosteric full agonist [3H]CP55,490, and reduces the binding of the orthosteric antagonist/inverse agonist [3H]SR141716A.
KEYWORDS: GAT211 | Supplier | CB1 ago-PAM | GAT-211 | GAT 211 | CAS [102704-40-5] | Cannabinoids | CB1 | Agonist | PAM | Receptors
3-(2-Nitro-1-phenylethyl)-2-phenylindole
[102704-40-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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