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Axon 4118
CAS [2400954-58-5]
MF C11H8F2IN5O2MW 407.12
CU-76 is a human cGAS (hcGAS) inhibitor with high binding affinity (IC50 value of 0.24 µM). CU-76 selectively inhibits the DNA pathway in human cells but has no effect on the RIG-I-MAVS or Toll-like receptor pathways.
KEYWORDS: CU-76 | Supplier | hcGAS inhibitor | CU76 | CU 76 | CAS [2400954-58-5] | cGAS–STING pathway | GTP-ATP | STING | Inhibitor | Enzymes | Proteins | Cyclic GMP-AMP synthase | Innate immune system
Methyl 4-amino-6-(3,5-difluoro-4-iodophenylamino)-1,3,5-triazine-2-carboxylate
[2400954-58-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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