TREK

K+ channels with two-pore domain (K2P) form a large family of hyperpolarizing channels. They produce background currents that oppose membrane depolarization and cell excitability. They are involved in cellular mechanisms of apoptosis, vasodilatation, anesthesia, pain, neuroprotection and depression. TREK-1 (K2P2.1), TREK-2 (K2P10.1), and TRAAK (TWIK Related Arachidonic acid Activated K+ channel) (K2P4.1), compose the TREK subfamily of K2P channels.[1]


[1] J. Noël et al. Molecular regulations governing TREK and TRAAK channel functions. Channels (Austin). 2011 Sep-Oct;5(5):402-9.

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Axon ID Name Description From price
2872 ML 335 Selective activator of the TREK-1 and TREK-2 potassium channel €110.00

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