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Featured Products
Axon 4111
CAS [2681302-83-8]
MF C16H12F3N5OMW 347.30
TMDJ-035 is a first highly potent and selective RyR2 inhibitor with an EC50 value of 0.013 μM. TMDJ-035 suppressed abnormal Ca2+ waves and transients in cardiomyocytes from a mouse model with RyR2(R420W) mutation. The inactive analog TMDJ-011 is available as Axon 4213.
KEYWORDS: TMDJ-035 | Supplier | RyR2 inhibitor | TMDJ035 | TMDJ 035 | CAS [2681302-83-8] | Calcium | Inhibitor
2-(5-(3,5-Difluorophenyl)-2H-tetrazol-2-yl)-N-(4-fluorophenyl)-N-methylacetamide
[2681302-83-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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