Ropidoxuridine - IPdR | 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodo-2-pyrimidinone

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 3953

CAS [93265-81-7]

MF C9H11IN2O4
MW 338.10

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in water and DMSO

Ropidoxuridine

Description

Ropidoxuridine is an orally available, halogenated thymidine (TdR) analog and is a potential radiosensitizer for use in human tumors. Ropidoxuridine is a prodrug that is efficiently converted to IUdR (5-iodo-2'-deoxyuridine), an intravenous radiosensitizer by a hepatic aldehyde oxidase.

Keywords: Ropidoxuridine | Supplier | Thymidine analog | IPdR | 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodo-2-pyrimidinone | CAS [93265-81-7] | Thymidylate pathway | Non Selective | Sensitiser | Sensitizer | Tumor

Thymidine analog; Radiosensitizer

Chemical name

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one

Parent CAS No.

[93265-81-7]

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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