NUC-7738 - 3’‑Deoxyadenosine 5’‑O‑phenyl‑(benzoxy‑L‑alaninyl)‑phosphate

Based on 4 reference(s) in Google Scholar 8 10 4

Axon 3826

CAS [2348493-39-8]

MF C26H29N6O7P
MW 568.52

  • Purity: 99%
  • Optical purity: Mixture of diastereomers
  • Soluble in DMSO and EtOH



The ProTide NUC-7738 is a phosphoramidate prodrug of Cordycepin (3’-dA, Axon 3825) and showed potent cytotoxic activity against a panel of hematological cancer cell lines. Moreover, NUC-7738 was able to bypass the premature breakdown, the poor uptake, and the kinase dependence for phosphorylation of the parental nucleoside. NUC-7738 promotes proapoptotic pathways and attenuates NF-kB.

KEYWORDS: NUC-7738 | Supplier | Anticancer agent | 3’-Deoxyadenosine 5’-O-phenyl-(benzoxy-L-alaninyl)-phosphate | NUC 7738 | NUC7738 | CAS [2348493-39-8] | Adenosine | Non Selective | Inhibitor | Advanced solid tumor | Lymphoma | ProTide | Prodrug

Size Unit Price Stock
5 mg €160.00 In Stock
25 mg €620.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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