PTI-125 dihydrochloride - Simufilam

Based on 7 reference(s) in Google Scholar 8 10 7

Axon 3746

CAS [2480226-06-8]

MF C15H21N3O.2HCl
MW 332.27

  • Purity: 99%
  • Soluble in water and DMSO
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PTI-125 dihydrochloride

Description

PTI-125 dihydrochloride is an orally available molecule targeting filamin A (FLNA). By binding FLNA with high affinity, PTI-125 prevents Aβ(42)'s toxic cascade, decreasing phospho-tau and Aβ aggregates and reducing the dysfunction of α7nAChRs, NMDARs, and insulin receptors.

KEYWORDS: PTI-125 dihydrochloride | Supplier | FLNA ligand | Simufilam | PTI125 | PTI 125 | CAS [2480226-06-8] | [1224591-33-6] | [2480226-07-9] | [2375909-85-4] | Amyloids | Filamin | Ligand | Proteins | Alzheimer's disease (AD) | Amyloid-β | Aβ42 | Neurodegeneration | Neuroinflammation

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5 mg €120.00 In Stock
25 mg €400.00 In Stock
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2 x 5 mg €180.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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