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Axon 3746
CAS [2480226-06-8]
MF C15H21N3O.2HClMW 332.27
PTI-125 dihydrochloride is an orally available molecule targeting filamin A (FLNA). By binding FLNA with high affinity, PTI-125 prevents Aβ(42)'s toxic cascade, decreasing phospho-tau and Aβ aggregates and reducing the dysfunction of α7nAChRs, NMDARs, and insulin receptors.
KEYWORDS: PTI-125 dihydrochloride | Supplier | FLNA ligand | Simufilam | PTI125 | PTI 125 | CAS [2480226-06-8] | [1224591-33-6] | [2480226-07-9] | [2375909-85-4] | Amyloids | Filamin | Ligand | Proteins | Alzheimer's disease (AD) | Amyloid-β | Aβ42 | Neurodegeneration | Neuroinflammation
1-Benzyl-8-methyl-1,4,8-triazaspiro[4.5]decan-2-one dihydrochloride
[1224591-33-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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