Naftifine hydrochloride

Based on 193 reference(s) in Google Scholar 8 10 193

Axon 3656

CAS [65473-14-5]

MF C21H21N.HCl
MW 323.86

  • Purity: 99%
  • Soluble in water, DMSO and EtOH

Naftifine hydrochloride


Naftifine hydrochloride is a topical antifungal agent against a broad spectrum of dermatophyte fungi and provides good activity against Candida and Aspergillus species. Fungicidal activity is attributed to inhibition of squalene epoxidase (SE), which prevents production of ergosterol and leads to toxic accumulation of squalene. Naftifine is also effective against gram-negative and gram-positive bacteria.

KEYWORDS: Naftifine hydrochloride | Supplier | Antifungal agent | CAS [65473-14-5] | [65472-88-0] | Antifungal | Dermatomycose

Topical broad-spectrum antifungal agent

Chemical name

(E)-N-Methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine hydrochloride

Parent CAS No.


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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

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