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Naftifine hydrochloride
Axon 3656
- Parent CAS: 65472-88-0
Purity:
99%
- Soluble in water, DMSO and EtOH
- MF: C21H21N.HCl
- MW: 323.86
Description
Naftifine hydrochloride is a topical antifungal agent against a broad spectrum of dermatophyte fungi and provides good activity against Candida and Aspergillus species. Fungicidal activity is attributed to inhibition of squalene epoxidase (SE), which prevents production of ergosterol and leads to toxic accumulation of squalene. Naftifine is also effective against gram-negative and gram-positive bacteria.
More Information
| Parent CAS No. | 65472-88-0 |
|---|---|
| Chemical Name | (E)-N-Methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine hydrochloride |
| SMILES | C1C=C2C(CN(C)C/C=C/C3C=CC=CC=3)=CC=CC2=CC=1.Cl |
| MFCD | MFCD00059047 |
| InChi | InChI=1S/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20;/h2-15H,16-17H2,1H3;1H/b11-8+; |
| InChiKey | OLUNPKFOFGZHRT-YGCVIUNWSA-N |
| CID | 5281098 |
| Short Description | Antifungal agent |
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