UCSF678 dihydrochloride - 5A6-78

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3636

CAS [N.A.]

MF C15H18N2O2S.2HCl
MW 363.30

  • Purity: 99%
  • Soluble in water, DMSO and EtOH

UCSF678 dihydrochloride


UCSF678 is an arrestin-biased subtype-selective 5-HT5A receptor partial agonist (Ki value of 42 nM). UCSF678 shows a more restricted off-target profile and decreased assay liabilities versus SB-699551 (Axon 1469). The control probe UCSF686 is availalbe as Axon 3635 and the inactive control probe, UCSF648 is available as Axon 3634.

KEYWORDS: UCSF678 dihydrochloride | Supplier | 5-HT5A partial agonist | 5A6-78 | UCSF 678 | UCSF-678 | CAS [2361697-55-2] | Serotonin | 5-HT5A | Receptors

Selective 5-HT5A receptor partial agonist

Chemical name

1-(1-(Methylsulfonyl)cyclopropyl)-N-(quinolin-8-ylmethyl)methanamine dihydrochloride

Parent CAS No.


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5 mg €130.00 In Stock
25 mg €490.00 In Stock
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2 x 5 mg €220.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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