Fludarabine - 9-β-D-Arabinofuranosyl-2-fluoroadenine | F-ara-A

Based on 7318 reference(s) in Google Scholar 8 10 7318

Axon 3457

CAS [21679-14-1]

MF C10H12FN5O4
MW 285.23

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO
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Fludarabine

Description

Fludarabine, a nucleoside analogue, inhibits DNA synthesis in proliferating cells; however, in indolent cells fludarabine has an inhibitory effect on RNA transcription. Additionally, Fludarabine prevents smooth muscle proliferation in vitro and neointimal hyperplasia in vivo through specific inhibition of STAT-1 activation.

KEYWORDS: Fludarabine | Supplier | DNA synthesis inhibitor | 9-β-D-Arabinofuranosyl-2-fluoroadenine | F-ara-A | CAS [21679-14-1] | DNA-RNA | STAT1 | Inhibitor | Transcription Factors | B-cell lymphocytic leukemia | Hairy cell leukaemia | Indolent lymphoma | Multiple myeloma

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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