Based on 2 reference(s) in Google Scholar 8 10 2

Axon 3394

CAS [199735-88-1]

MF C15H13Cl2NO3
MW 326.17

  • Purity: 98%
  • Soluble in 0.1N NaOH(aq), DMSO and EtOH



CADD522 is a potent inhibitor of RUNX2-DNA binding with an IC50 value of 10 nM. In vitro and in vivo studies reveal that CADD522 suppresses breast cancer growth and metastasis. Additionally, CADD522 inhibits mitochondrial oxidative phosphorylation by decreasing the mitochondrial oxygen consumption rate (OCR) and ATP production in human breast cancer cells in a RUNX2-independent manner.

KEYWORDS: CADD522 | Supplier | RUNX2-DNA inhibitor | CADD 522 | CADD-522 | CAS [199735-88-1] | DNA-RNA | CBF | Inhibitor | Transcription Factors | Breast cancer

Size Unit Price Stock
10 mg €90.00 In Stock
50 mg €290.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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