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Enzymes
EC 4.1.1.50
Sardomozide dihydrochloride

Sardomozide dihydrochloride - CGP48664A | CGP48664 dihydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3290

CAS [138794-73-7]

MF C11H14N6.2HCl
MW 303.19

Purity: 98%
Soluble in water and DMSO

Sardomozide dihydrochloride

Description

Sardomozide dihydrochloride is a potent and selective inhibitor of S-Adenosylmethionine decarboxylase (SAMDC) with an IC50 value of 5 nM.

KEYWORDS: Sardomozide dihydrochloride | Supplier | SAMDC inhibitor | CGP48664A | CGP48664 dihydrochloride | CGP 48664A | CGP-48664A | CGP-48664 | CGP 48664 | CAS [138794-73-7] | [149400-88-4] | S-adenosylmethionine | Decarboxylase | Inhibitor | Enzymes | Polyamine biosynthesis

J Stanek et al. 4-Amidinoindan-1-one 2'-amidinohydrazone: a new potent and selective inhibitor of S-Adenosylmethionine decarboxylase. J Med Chem. 1993;36(15):2168-2171.

U Regenass et al. CGP 48664, a new S-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activity. Cancer Res. 1994 Jun 15;54(12):3210-7.

Cell Signaling & Oncology Miscellaneous EC 4.1.1.50

Potent and selective SAMDC inhibitor

Chemical name

2-(4-Carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide dihydrochloride

Parent CAS No.

[149400-88-4]

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