Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3281

CAS [2369979-68-8]

MF C19H20ClFN4
MW 358.84

  • Purity: 99%
  • Soluble in 0.1N HCl(aq), DMSO and EtOH



JHU37160 is a potent DREADD agonist with hM3Dq and hM4Di Ki values of 1.9 nM and 3.6 nM, respectively; and with hM3Dq and hM4Di EC50 values of 18.5 nM and 0.2 nM, respectively. JHU37160 is a first DREADD agonist with high in vivo potency for CNS applications.

KEYWORDS: JHU37160 | Supplier | DREADD agonist | JHU 37160 | JHU-37160 | CAS [2369979-68-8] | [2576356-03-9] | Acetylcholine | DREADD | Agonist | Receptors | Designer receptors exclusively activated by designer drug | Chemogenetic technology | Neurotheranostics

Potent and CNS-active DREADD agonist

Chemical name


Parent CAS No.


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5 mg €90.00 In Stock
25 mg €300.00 In Stock
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2 x 5 mg €140.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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