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JHU37152
Axon 3280
CAS:
2369979-67-7
Purity:
99%
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C19H20ClFN4
- MW: 358.84
Description
JHU37152 is a potent, selective and brain-penetrant DREADD agonist with Ki values of 1.8 nM and 8.7 nM for hM3Dq and hM4Di, respectively.
More Information
| Parent CAS No. | 2369979-67-7 |
|---|---|
| Chemical Name | 8-Chloro-11-(4-ethylpiperazin-1-yl)-1-fluoro-5H-dibenzo[b,e][1,4]diazepine |
| SMILES | N1C2C=C(Cl)C=CC=2NC2C=CC=C(F)C=2C=1N1CCN(CC)CC1 |
| MFCD | N.A. |
| InChi | InChI=1S/C19H20ClFN4/c1-2-24-8-10-25(11-9-24)19-18-14(21)4-3-5-16(18)22-15-7-6-13(20)12-17(15)23-19/h3-7,12,22H,2,8-11H2,1H3 |
| InChiKey | NZMZJNNWMSYDNX-UHFFFAOYSA-N |
| CID | 139033721 |
| Short Description | DREADD agonist |
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