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Axon 2858
CAS [945714-67-0]
MF C20H22ClNOMW 327.85
FPS-ZM1 is a high-affinity RAGE-specific inhibitor (Ki value of 25 nM) which binds specifically to the V domain of RAGE, crosses the BBB, and inhibits Aβ-induced cellular stress in RAGE-expressing cells in vitro and in brain in vivo. FPS-ZM1 was not toxic to cells and mice.
KEYWORDS: FPS-ZM1 | supplier | RAGE inhibitor | FPS ZM1 | FPSZM1 | CAS [945714-67-0] | AGE | RAGE | Inhibitor | Receptors | Alzheimer's disease | Amyloid β peptide | Aβ
N-Benzyl-4-chloro-N-cyclohexylbenzamide
[945714-67-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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