BAM15 is a mitochondrial protonophore uncoupler, which does not depolarize the plasma membrane. Compared to FCCP, an uncoupler of equal potency, BAM15 treatment of cultured cells stimulates a higher maximum rate of mitochondrial respiration and is less cytotoxic. Furthermore, BAM15 is bioactive in vivo and dose-dependently protects mice from acute renal ischemic-reperfusion injury.

KEYWORDS: BAM15 | supplier | Mitochondrial uncoupler | BAM 15 | BAM-15 | CAS [210302-17-3] | Proton | Ionophore (proton) | Ionophore | Unclassified