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Axon 2736
CAS [210302-17-3]
MF C16H10F2N6OMW 340.29
BAM15 is a mitochondrial protonophore uncoupler, which does not depolarize the plasma membrane. Compared to FCCP, an uncoupler of equal potency, BAM15 treatment of cultured cells stimulates a higher maximum rate of mitochondrial respiration and is less cytotoxic. Furthermore, BAM15 is bioactive in vivo and dose-dependently protects mice from acute renal ischemic-reperfusion injury.
KEYWORDS: BAM15 | supplier | Mitochondrial uncoupler | BAM 15 | BAM-15 | CAS [210302-17-3] | Proton | Ionophore (proton) | Ionophore | Unclassified
N5,N6-Bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
[210302-17-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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