Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2700

CAS [1798328-24-1]

MF C24H16N4
MW 360.41

  • Purity: 99%
  • Soluble in DMSO



The CIP2A inhibitor TD52 had more potent apoptotic effects than erlotinib (Axon 1128) in HCC cells (IC50 values of 0.9, 0.9, 0.8 and 1.2 μM in HA22T, Hep3B, PLC5 and Sk-Hep1 cell lines, respectively). Also, CIP2A-dependent p-Akt downregulation mediates TD52-induced apoptosis in TNBC. TD52-induced tumor inhibition was associated with reactivation of PP2A and downregulation of CIP2A and p-Akt in vivo.

KEYWORDS: TD52 | supplier | CIP2A inhibitor | TD 52 | TD-52 | CAS [1798328-24-1] | PP2A | CIP2A | Inhibitor | Proteins | p90 | KIAA1524 | HCC | TNBC

Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €325.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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