AX-024 hydrochloride

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2692

CAS [1704801-24-0]

MF C21H22FNO2.HCl
MW 375.86

  • Purity: 99%
  • Soluble in water and DMSO
Recently added

AX-024 hydrochloride

Description

First-in-class inhibitor of T cell receptor (TCR); AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). By modulating TCR signaling, the inhibitor prevented the development of psoriasis and asthma and, furthermore, exerted a long-lasting therapeutic effect in a model of autoimmune encephalomyelitis.

KEYWORDS: AX-024 hydrochloride | supplier | T cell receptor inhibitor | AX024 hydrochloride | AX 024 hydrochloride | AX-024 | AX024 | AX 024 | Ax24 | CAS [1704801-24-0] | [1370544-73-2] | Antigen | T cell | Inhibitor | Receptors | TCR | Autoimmune | Nck | TCR-Nck | Psoriasis | Asthma | Encephalomyelitis

Order
Size Unit Price Stock
5 mg €125.00 In Stock
25 mg €435.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €200.00 In Stock
2 x 25 mg €700.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...