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Hydroxychloroquine sulfate
- NSC 4375
- Parent CAS: 118-42-3
- Soluble in water
- MF: C18H26ClN3O.H2SO4
- MW: 433.95
Description
Antimalarial drug (HCQ) and immunosuppressive lysosomotropic amine, also used as a slow-acting anti-rheumatic drug and for treatment of lupus erythematosus. HCQ is also shown to act as an antagonist for Toll-like receptors (TLR-7 and TLR-9) in plasmacytoid dendritic cells (pDCs).
More Information
| Parent CAS No. | 118-42-3 |
|---|---|
| Chemical Name | 2-((4-(7-chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol sulfate |
| SMILES | C(N(CC)CCO)CCC(NC1C2C(N=CC=1)=CC(Cl)=CC=2)C.S(O)(=O)(O)=O |
| MFCD | MFCD00078203 |
| InChi | InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4) |
| InChiKey | JCBIVZZPXRZKTI-UHFFFAOYSA-N |
| CID | 12947 |
| Short Description | Antimalarial drug |
References
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