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Receptors
GPCR
Serotonin
5-HT1F
LY 334370 hydrochloride

LY 334370 hydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1612

CAS [199673-74-0]

MF C21H22FN3O.HCl
MW 387.88

Purity: 99%
Soluble in water and DMSO

LY 334370 hydrochloride

Description

Selective 5-HT1F receptor agonist with Ki value to be 1.87 nM

DS Dupuis et al. G-protein activation at 5-HT1A receptors by the 5-HT1F ligand LY-334,370 in guinea-pig brain sections and recombinant cell lines. Br. J. Pharmacol. 1998, 124(2), 283–90.

S Shepheard et al. Possible antimigraine mechanisms of action of the 5HT1F receptor agonist LY-334,370. Cephalalgia 1999, 19(10), 851-858.

CNS 5-HT1F A19

5-HT1F antagonist

Chemical name

4-fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benzamide hydrochloride

Parent CAS No.

[182563-08-2]

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Size	Unit Price	Stock
10 mg	€115.00	In Stock
50 mg	€450.00	In Stock

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