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SB 699551 dihydrochloride
- SB 699551A
Axon 1469
- Parent CAS: 864741-95-7
Purity:
99%
- Soluble in DMSO
- MF: C34H45N3O.2HCl
- MW: 584.66
Description
Selective 5-HT5A receptor antagonist
More Information
| Parent CAS No. | 864741-95-7 |
|---|---|
| Chemical Name | 3-Cyclopentyl-N-(2-dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-propionamide dihydrochloride |
| SMILES | C1C=C(CN(C(=O)CCC2CCCC2)CCN(C)C)C=CC=1C1C=CC(CNCCC2C=CC=CC=2)=CC=1.Cl.Cl |
| MFCD | MFCD11112202 |
| InChi | InChI=1S/C34H45N3O.2ClH/c1-36(2)24-25-37(34(38)21-16-28-10-6-7-11-28)27-31-14-19-33(20-15-31)32-17-12-30(13-18-32)26-35-23-22-29-8-4-3-5-9-29;;/h3-5,8-9,12-15,17-20,28,35H,6-7,10-11,16,21-27H2,1-2H3;2*1H |
| InChiKey | QJMKBIHLMPTYTI-UHFFFAOYSA-N |
| CID | 11983346 |
| Short Description | 5-HT5A antagonist |
References
- DF Corbett et al. Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry. Bioorg. Med. Chem. Letts. 2005, 15, 4014.
- DR Thomas et al. SB-69951-A , a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: evidence for an autoreceptor role for the 5-ht5A receptor in guinea pig brain. Neuropharmacology 2006, 51, 566.
- DR Thomas. 5-ht5A receptors as a therapeutic target. Pharmacol. Ther. 2006, 111, 707.
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