Actinobolin sulfate
Axon N0047
- Parent CAS: 24397-89-5
- Optical Purity: Optically pure
- Soluble in water and DMSO
- MF: 2C13H20N2O6·H2O4S
- MW: 349.35
Description
Antimicrobal agent€ protein and DNA Synthesis Inhibitor.******Source information: Streptomyces sp.
More Information
| Parent CAS No. | 24397-89-5 |
|---|---|
| Chemical Name | (S)-2-Amino-N-((3R,4R,4aR,5R,6R)-5,6,8-trihydroxy-3-methyl-1-oxo-3,4,4a,5,6,7-hexahydro-1H-isochromen-4-yl)propanamide |
| SMILES | C[C@@H]1[C@@H]([C@@H]2[C@H]([C@@H](CC(=C2C(=O)O1)O)O)O)NC(=O)[C@H](C)N.C[C@@H]1[C@@H]([C@@H]2[C@H]([C@@H](CC(=C2C(=O)O1)O)O)O)NC(=O)[C@H](C)N.OS(=O)(=O)O |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | Protein and DNA Synthesis Inhibitor |
References
- TH Haskell et al.Actinobolin and its fermentative production. US Patent 1962 US3043830
- FJ Antosz et al. The structure and chemistry of actinobolin. J Am Chem Soc. 1970 Aug 12;92(16):4933-42.
- PJ Armstrong Jr. et al. In vitro evaluation of actinobolin as an antibiotic for the treatment of periodontal disease. Appl Microbiol. 1972 Jan;23(1):88-90.
- DE Hunt et al. The effect of actinobolin on nucleic acid and protein synthesis in Escherichia coli. Can J Microbiol. 1966 Jun;12(3):515-20.
- D Smithers et al. Inhibiton of protein synthesis in mammalian cells by actinobolin. Mol Pharmacol. 1969 Sep;5(5):433-45.
