Vanoxonin
Axon N0042
CAS:
86933-99-5
- Optical Purity: Optically pure
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C18H25N3O9
- MW: 427.41
Description
Strong thymidylate synthase inhibitor.******Source information: Saccharopolyspora hirusta MG245-CF2Strong thymidylate synthase inhibitorSaccharopolyspora hirusta MG245-CF2
More Information
| Parent CAS No. | 86933-99-5 |
|---|---|
| Chemical Name | (S)-2-((2S,3R)-2-(2,3-dihydroxybenzamido)-3-hydroxybutanamido)-5-(N-hydroxyacetamido)pentanoic acid |
| SMILES | C1(O)C(O)=C(C(=O)N[C@H](C(N[C@@H](CCCN(O)C(=O)C)C(=O)O)=O)[C@@H](C)O)C=CC=1 |&1:8,11,24,r| |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | thymidylate synthase inhibitor |
References
- F Kanai et al. Vanoxonin, a new inhibitor of thymidylate synthetase. J Antibiot (Tokyo). 1983 Jun;36(6):656-60.
- F Kanai F et al. Vanoxonin, a new inhibitor of thymidylate synthetase. II. Structure determination and total synthesis. J Antibiot (Tokyo). 1985 Jan;38(1):31-8.
- F Kanai F et al. Vanoxonin, a new inhibitor of thymidylate synthetase. III. Inhibition of thymidylate synthetase by vanoxonin-vanadium complex.
