Iturin A-2
- KRF 001A
Axon N0028
CAS:
83785-07-3
- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C48H74N12O14
- MW: 1043.18
Description
Antifungal antitumor.******Source information: Bacillus subtilisAntifungal antitumorBacillus subtilis
More Information
| Parent CAS No. | 83785-07-3 |
|---|---|
| Chemical Name | 2,2',2'-((3R,6S,9R,13S,16R,19R,22S,27aS)-22-(3-Amino-3-oxopropyl)-16-(4-hydroxybenzyl)-6-(hydroxymethyl)-1,4,7,11,14,17,20,23-octaoxo-9-undecylhexacosahydro-1H-pyrrolo[2,1-i][1,4,7,10,13,16,19,22]octaazacyclopentacosine-3,13,19-triyl)triacetamide |
| SMILES | CCCCCCCCCCC[C@H]1NC([C@H](CO)NC(=O)[C@@H](CC(=O)N)NC([C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CC(=O)N)NC(=O)[C@@H](CC2C=CC(O)=CC=2)NC(=O)[C@H](CC(N)=O)NC(=O)C1)CCC(=O)N)=O)=O |&1:11,14,20,27,34,38,46,58,r| |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | Active as antifungal and antitumor |
References
- O Asaka et al. Biocontrol of Rhizoctonia solani Damping-Off of Tomato with Bacillus subtilis RB14. Appl Environ Microbiol. 1996 Nov;62(11):4081-5.
- S Rong et al. Antifungal activity of endophytic Bacillus safensis B21 and its potential application as a biopesticide to control rice blast. Pestic Biochem Physiol. 2020 Jan;162:69-77.
- J Jiang et al. Production, Purification and Characterization of ‘Iturin A-2’ a Lipopeptide with Antitumor Activity from Chinese Sauerkraut Bacterium Bacillus velezensis T701. Int. J of Peptide Res. Therap. 2021, 27, 2135-2147.
